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Management of AEs GI AEs typically occur during initiation and uptitration, appearing as transient, mild-to-moderate symptoms

3.3 per 1,000 person-years

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Full-body workouts or upper/lower split

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This effectiveness is due to tirzepatides dual mechanism, acting as both a glucose-dependent insulinotropic polypeptide (GIP) and a glucagon-like peptide-1 (GLP-1) receptor agonist