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doi: 10.1016/j.lfs.2020.118546 199 JinXHeRLiuJWangYLiZJiangBet al

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Nutrition (Burbank, Los Angeles County, Calif.), 126 , Article 112516

Molecular profiling data have greatly facilitated the identification of candidate gene driver alterations in GC, such as gene mutations, chromosomal alterations, transcriptional changes, and dysregulated epigenetic modifications 2,3

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For the OGD phase, cells were washed twice with PBS and then incubated in glucose-free DMEM (Gibco, Thermo Fisher Scientific, Waltham, MA, United States) under hypoxic conditions (1% O 2 , 94% N 2 , 5% CO 2 ) in a hypoxia chamber (BioSpherix, Parish, NY, United States) for 8 h