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Peptide therapeutics: Current status and future directions

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Introduction The development of new compounds in recent decades has substantially improved the pharmacotherapy of type 2 diabetes (T2D) by improving achievement of metabolic targets while mitigating specific side effects (e.g., weight gain, hypoglycemia) frequently observed in patients treated with traditional hypoglycemic drugs such as insulin and sulfonylureas

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doi:10.1016/s0006-3223(97)00277-1