Sources of depletion can include: Mitochondrial energy production (a normal and essential process, but creates harmful byproducts like ROS) Chronic infections, gut dysbiosis (including SIBO and Candida ), and ongoing inflammation Air pollution, heavy metals, and environmental toxins 17 Ultra-processed foods, sugar-sweetened beverages, and foods high in advanced glycation end products (heavily browned foods) 18 Pesticides and herbicides 19 Alcohol and smoking Psychological stress Even vigorous exercise (a healthy stressor that still creates oxidative byproducts) 20 Understanding this helps explain why simply eating well sometimes isnt enough, and why targeted nutritional strategies make a meaningful difference
The Pinealon peptide benefits article covers this peptide in greater detail
Speak with your doctor about whether compounded HRT could be an option
Current Opinion in Neurobiology, 4(5), 696-702.
Australian labs report serum vitamin B12 in picomoles per litre (pmol/L)
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