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The study will last for about 17-32 weeks Participants will have at least 5 in-house visits (where participants will stay at the clinic) and 17 out A Trial Investigating the Pharmacokinetic and Pharmacodynamic Properties of Insulin Icodec in Subjects With Type 2 Diabetes Intervention 1 Not provided Anticipated Start Date Not provided Actual Start Date 2020-10-16 Anticipated Date of Last Follow-up 2023-09-14 Estimated Primary Completion Date Not provided Estimated Completion Date Not provided Actual Primary Completion Date 2022-04-22 Actual Completion Date 2022-04-22 Age Cohort Genders Accepts pregnant individuals Unspecified Accepts lactating individuals Unspecified Accepts healthy individuals No Inclusion Criteria: * Male or female * Aged 18-75 years (both inclusive) at the time of signing informed consent * Body mass index between 18.0 and 38.0 kg/m\^2 (both inclusive) * HbA1c (glycated haemoglobin) below or equal to 9 percentage (75 mmol/mol) at screening * Current daily basal insulin treatment greater than or equal to 0.2 (I)U/kg/day with or without any of the following anti-diabetic drugs/regimens with stable doses greater than or equal to 90 days prior to the day of screening: 1) Any metformin formulation 2) Other oral antidiabetic drugs: DPP-4 nhibitors / SGLT2 inhibitors / Oral combination products (for the allowed individual oral antidiabetic drugs) * Oral or injectable GLP-1 Receptor Agonists Exclusion Criteria: * Known or suspected hypersensitivity to trial product(s) Not provided Interventional (clinical trial) 46 Not provided Single group assignment Not provided Open label Not provided Treatment NCT05790681 Phase I Completed Novo Nordisk A/S Insulin icodec is a new medicine which is under development for use in humans and is not yet available at the pharmacy

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Munne-Bosch, S., Mueller, M., Schwarz, K