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The reduction in oestrogen has two primary effects that contribute to this weight gain: Slowed Metabolism: A decrease in oestrogen slows down our metabolism, making it harder for the body to burn calories efficiently

These medications work by mimicking the effects of the natural hormone GLP-1, enhancing insulin secretion, suppressing appetite, and slowing gastric emptying

Efficacy Studies Efficacy studies are a critical component of clinical trials

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Its seven-day half-life enables once-weekly dosing, and it reaches steady state at any given dose in approximately four to five weeks

In many cases, this addresses the entirety of the problem, and no further treatment (medical or otherwise) is necessary