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VerfaillieSCJAdriaanseSMBinnewijzendMAABenedictusMROssenkoppeleRWattjesMPet al

It functions as a chloride-dependent urate transporter, which is involved in sodium/phosphate cotransport activities

Studies using the GABA analog in Fmr1 knockout mice demonstrated corrections in hyperactivity and modulation of altered sensory-motor gating, measured as increased prepulse inhibition following acute treatment, by enhancing the activity of extrasynaptic GABA receptors, thereby improving anxiety, aggression, and repetitive behavioral abnormalities in FXS mice (71)

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