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Impact of the MTHFR C677T polymorphism on colorectal cancer in a population with low genetic variability

Some studies suggest that the vitamin may even help prevent cognitive decline

We detected known (G3BP1) and novel structural alterations of proteins from stress granules as well as from nuclear speckles and validated alteration of nuclear speckles by fluorescence microscopy and of the protein SERBP1 by polysome profiling

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Multiomics approaches and gut-on-a-chip microfluidic systems may clarify whether modifying microbial composition can enhance drug efficacy or reduce variability, potentially supporting tailored therapy rather than trial-and-error prescribing