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Tsuchida S, Matsusaka T, Chen X, Okubo S, Niimura F, Nishimura H, Fogo A, Utsunomiya H, Inagami T, Ichikawa I

Must maintain rigorous hygiene standards

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The primary mechanism involves intrinsic factor binding in the stomach, while a secondary pathway allows small amounts to absorb through passive diffusion

Oral dosing is preferred for gut conditions and is taken on an empty stomach