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Over 139,000 peer-reviewed scientific articles have addressed this powerhouse molecule, and experts are now recognizing that an alarming rate of people are deficient for a variety of reasons, including chronic stress, environmental toxins and excessive use of antibiotics

The study characterized the compounds selectivity for NNMT over other methyltransferases [1]

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Mittal VA, Vargas T, Osborne KJ, et al

Many inflammatory chemokines are mainly produced by synovial macrophages and FLS in the joints of RA patients, whereas CX3CL1 is produced by synovial endothelial cells