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To reduce these potential risks, healthcare providers are advised to closely monitor patients, particularly those with a history of gallbladder or biliary disease [49]

This recommendation is based on the lack of human safety data and concerns about potential risks to a developing fetus

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The theoretical advantage is smoother blood levels with less peak-to-trough variation, which may reduce the intensity of side effects, particularly nausea and appetite fluctuation

Accessed 5 Oct 2020

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