Larger, longer-term studies are needed to establish durability and optimal dosing
We proposed that by exploiting the abundant amount of reactive iron(II) in DTP cancer cells 6,7,8 , such a bifunctional molecule would form an active catalyst in the cell to promote the oxidative degradation of lysosomal membrane lipids and ultimately trigger ferroptosis
Vitamin C and infections
Nuttall SL, Kahn JN, Thorpe GH, Landford N, Kendall MJ: The impact of therapeutic doses of paracetamol on serum total anti-oxidant capacity
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It is suggested that GSSG accumulates because the capacity of GR is insufficient to keep up with H 2 O 2 -detoxifying enzymes, either because the latter have higher capacities or due to redundancy (APx, CAT, PRx)