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The third group received normal saline concomitantly with Dox and served as the disease control

Exendin-4 treatment (0.5 g/kg) resulted in a reduction of pro-inflammatory cytokines such as TNF- and IL-1 in CSF and in hippocampal and cortical brain areas (Ventorp et al., 2017)

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Research is derived from case reports which indicate that the risks associated with coffee enemas outweigh any perceived health benefits

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