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investigation, M.K., M.G., M.K.-K

The emergence of GIPR/GLP-1R co-agonists has fostered a growing interest in the actions of GIP and glucagon-like peptide-1 (GLP-1) in metabolically relevant tissues, including liver, muscle and adipose tissue, regarding the control of glucose and lipid homeostasis

Patients who self-administer without training may inject at incorrect depths, fail to properly sanitize the injection site, or reuse needles, all of which increase the risk of complications

While current research focuses predominantly on hepatocytes, potential Kupffer cell modulation in NASH-related inflammation and fibrosis warrants further investigation (78)

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Throughout life, melatonin levels tend to be significantly reduced